Popis Prostředku - COOK Medical OASIS Mode D'emploi

allowing fluid management to be controlled by secondary
dressing layers.
6. Assess the wound to determine moisture conditions and
apply appropriate secondary dressing layers to maintain
a moist wound environment. Change the secondary
dressing layers as needed to maintain a moist, clean
wound area.
NOTE: To prevent damage to the newly-incorporated OASIS
ECM, ensure that the non-adherent dressing (step 5) is only
changed when ready to assess the wound.
7. Discard any unused portions of unused OASIS ECM
according to institutional guidelines for biological waste.
Reapply, as needed, if the OASIS ECM is no longer visible.
Typically, reapplication is needed every 3-7 days until the
wound is re-epithelialized.
8. As healing occurs, sections of the OASIS ECM may
gradually peel. Carefully remove any remaining loose
product around the edge as needed.
IMPORTANT: If a gel forms on the wound surface, do not
attempt to forcibly remove it. Successful integration of the
OASIS ECM may form a caramel-colored or off-white gel. Do
not remove this gel by debridement. This caramelization
contains ECM, which continues to replace deficient and
missing ECM in the wound.
9. Gently cleanse the wound surface with sterile saline; leave
the ECM gel intact.
10. Carefully reassess the wound and record healing
progression and other relevant information.
REFERENCES
1. Shi L, Ronfard V. Biochemical and biomechanical
characterization of porcine small intestinal submucosa
(SIS): a mini review. Int J Burn Trauma. 2013;3:173-179.
2. Yeh DD, Nazarian RM, Demetri L, et al. Histopathological
assessment of OASIS Ultra on critical-sized wound healing:
a pilot study. J Cutan Pathol. 2017;44(6):523-529.
3. Romanelli M, Dini V, Bertone M, Barbanera S, Brilli C.
OASIS wound matrix versus Hyaloskin in the treatment of
difficult-to-heal wounds of mixed arterial/venous etiology.
Int Wound J. 2007;4(1):3-7.
4. Hodde J, Janis A, Ernst D, Zopf D, Sherman D, Johnson C.
Effects of sterilization on an extracellular matrix scaffold:
Part I. Composition and matrix architecture. J Mater Sci
Mater Med. 2007;18(4):537-543.
5. Hodde JP, Badylak SF, Brightman AO, Voytik-Harbin SL.
Glycosaminoglycan content of small intestinal submucosa:
A bioscaffold for tissue replacement. Tissue Eng. 1996;2(3):
209-217.
EXTRACELULÁRNÍ MATRICE OASIS®
POPIS PROSTŘEDKU
EXTRACELULÁRNÍ MATRICE OASIS® (ECM) je arch sušené
submukózy tenkého střeva (small intestinal submucosa, SIS)
používaný k ošetření ran s částečnou tloušťkou (zahrnujících
5
ČESKY